Obesity is a medical condition in which there is accumulation of excess fat leading to serious health hazards and reduced life expectancy. It is a leading preventable cause of increasing mortality and morbidity worldwide and has proved to be a global threat of 21st century. Pharmaceutical industries have been investing crores of rupees for development of anti-obesity agent but till date none of them have proved to be worthwhile in curbing the increasing epidemic of obesity. Recent advances made in understanding the mechanism of food intake and energy expenditure have made significant contribution in identifying potential targets for obesity treatment. Research on novel targets for obesity treatment may possibly help to curb the menace of obesity. As the current drug therapies pose serious adverse effects, the search for a novel drug continues.
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